Cart
sales@molnova.com
Home - Products - Chromatin/Epigenetic - HMTase - EPZ 025654

EPZ 025654

CAS No. 1888328-89-9

EPZ 025654 ( EPZ025654;EPZ-025654;GSK 35336023 )

Catalog No. M12957 CAS No. 1888328-89-9

EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 1413 Get Quote
50MG 2862 Get Quote
100MG 3870 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote
Group Booking Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    EPZ 025654
  • Note
    Research use only, not for human use.
  • Brief Description
    EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.
  • Description
    EPZ025654 (GSK 35336023) is a potent, selective arginine methyltransferase CARM1 inhibitor with IC50 of 3 nM.
  • Synonyms
    EPZ025654;EPZ-025654;GSK 35336023
  • Pathway
    Chromatin/Epigenetic
  • Target
    HMTase
  • Recptor
    HMTase
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1888328-89-9
  • Formula Weight
    577.09
  • Molecular Formula
    C29H33ClN8O3
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O[C@H](CNC)COC1=CC=C(Cl)C(C2=NC(C3=C(C)ON=C3C)=C(C)C(N4CC5=NC(N6CCC6)=NC=C5C4)=N2)=C1
  • Chemical Name
    (R)-1-(3-(4-(2-(azetidin-1-yl)-5,7-dihydro-6H-pyrrolo[3,4-d]pyrimidin-6-yl)-6-(3,5-dimethylisoxazol-4-yl)-5-methylpyrimidin-2-yl)-4-chlorophenoxy)-3-(methylamino)propan-2-ol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Drew AE, et al. Sci Rep. 2017 Dec 21;7(1):17993.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • MI-2-2 hydrochloride

    MI-2-2 hydrochloride is a potent inhibitor of the menin-MLL interaction that binds to menin with low nanomolar affinity (Kd=22 nM).

  • MM-589

    A highly potent, cell-permeable inhibitor of WDR5-MLL interaction with IC50 of 0.9 nM, Ki of <1 nM.

  • CMP-5

    CMP-5 (PRMT5-IN-5)is a first-in-class, small-molecule PRMT5-specific inhibitor that blocks EBV-driven B-lymphocyte transformation and survival.

Sign In Join Free